This is what has worked for me and I hope it works for you. I am using an AMD 5600 and RTX 2080 super. I have v-sync turned on in Nvidia control panel and off in-game, with no max fps in the control panel and the highest available in-game. (I used to have so many stutters it made me nauseous but this fixed it)
Turn off raytracing.
Have v-sync off in-game and force it through Nvidia control panel (or whatever the AMD equivalent is)
I have seen reports that above 60 fps causes mouse input issues, but for me, I have been playing around 100 fps for a couple of hours and had no issue
TL;DR Turn down textures and turn off ray tracing.
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